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Showing posts from September 8, 2009

CANCER GRADING AND STAGING METHODS-LESSON 107

Tumors are classified on the basis of their location, microscopic appearance, and extent of spread. Of particular importance are the tumor's GRADE that is the degree of maturity or differentiation under the microscope and STAGE that is the extent of spread within the body. These two properties influence the prognosis that is the chances of successful treatment and survival and determine the specific treatment to be used. When grading a tumor, the pathologist is concerned with the microscopic appearance of the tumor cells, specifically with their degree of maturation or differentiation. Often, four grades are used. Grade I tumors are very well differentiated, so that they closely resemble the normal parent tissue of their origin. Grade IV tumors are so undifferentiated or anaplastic that even recognition of the tumor's tissue of origin may be difficult. Grade II and III are intermediate in appearance, moderately or poorly differentiated, as opposed to well differentiate

CANCER PATHOLOGY EXPLANATIONS-2-LESSON 106

TYPES OF TUMORS AND THEIR ORIGINS:   1. Alveolar: Tumor cells outline prototypes bearing resemblance to tiny and microscopic pouches. They are normally brought into being in tumors of muscle, bone, fat, and cartilage. 2. Carcinoma in situ: This microscopic term of cancer refers to confined to a small area and tumor cells that have not marched into neighboring formations. Cervical cancer of possibly will start in on at the same time as carcinoma in situ. 3. Diffuse: Distribution in an even way all the way through the affected tissue. Malignant lymphomas may display diffuse attachment of lymph nodes. 4. Dysplastic: With reference to atypical development of cells. These tumors exhibit a exceedingly abnormal other than not obviously cancerous look. Dysplastic nevi such as moles of skin are the examples of this type. 5. Epidermoid: Similar to squamous epithelial cells. They are thin and plate-like. They are over and over again taking place in the respiratory tract.